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Cannabinoids in the Treatment of Epilepsy

CBD

Globally, cannabis is one of the most widely used recreational drugs. It comes in several variations and has been used for medical purposes such as treatment or management of numerous diseases. Also, people use the drug for recreational purposes to achieve the feeling of becoming high. However, class B that is possession and distribution for recreational purposes is illegal. Notably, medical cannabis is sold as cannabidiol (CBD) oil where marijuana plants contribute to the significant cannabinoid contents. However, CBD oil does not always contain tetrahydrocannabinol (THC) which is a highly psychoactive ingredient of cannabis. Therefore, here is what you need to know about treating epilepsy with CBD oil:

CBD Oil for Epilepsy

Reportedly, CBD oil has several health benefits, suchgummies as treating epilepsy. Notably, epilepsy drugs do not work well or sometimes fail to work entirely as about one-third of the population suffering from the condition. Regrettably, epilepsy that is hard to treat is often associated with increased risk of premature deaths. Therefore, studies suggest that CBD oil helps people with epilepsy to control the seizures and eventually save their lives. Similarly, one can add cannabis oil to the existing medication for effective treatment in devastating epilepsy among child and adolescents.

How it Works

CBD oil has two primary constituents, that is THC (tetrahydrocannabinol) and CBD (cannabidiol). CBD oil has low quantities of THC. However, THC has no medicinal value and considered as a schedule 1 drug. Therefore, CBD oil cannot produce the psychoactive results of cannabis that THC does. Hence, one should carefully administer it in controlled ways for practical use. Through animal studies, the researchers deduced that endocannabinoid production increases the overexpression of cannabinoid receptors (CB1) which compensates excitotoxic effects that enhance the glutamate activity.

Additionally, Cannabidiolic acid (CBDA) has anti-seizure activity through different mechanisms that bind serotonin receptors (5-HT1A) 100-fold. The mechanisms become achievable by lowering CBD oil dosage and combining it with THC oil. The seizures occur because of unusual electrical activity in the brain, which spreads and causes uncontrollable physical movements. The anti-seizure drugs work by decelerating excitatory nerve commotion in mind. Similarly, CBD reduces some types of seizure as it has biochemical effects on the nerve cells on the brains, which has impacts on the seizures.…